Disease Classification
Drs. Paul Wise and Atul Butte both felt dissatisfied with current classification schemes of disease, with Dr. Wise finding the current debate between genetic and environmental causes of disease was an artificial distinction to make for his work in Public Policy, and Dr. Butte realizing that current disease classifications were nearly a hundred years old, and barely updated to take advantage of the discoveries in his field of Genomics and Bioinformatics. The duo received pilot funding through the Stanford Center for Biomedical Ethics, funded by NHGRI, to build a master map of known gene-environment-disease relations and to study the graphical properties of this map. Initial findings from this pilot work have shown that searching for disease, gene, and environmental hubs in this map will enable new discoveries in terms of the shared etiology of disease and new thinking about the nature of gene-environmental interactions in disease, relatable to public policy initiatives.
More information about the Phenome-Genome network.
Project Directors:
Atul Butte, MD, PhD
Assistant Professor of Medicine and Pediatrics
(bio/cv)
Paul Wise, MD, MPH
Professor of Child Health and Society
(bio/cv)
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